abstract：:Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic lung disease with no clear etiology and few therapeutic options. Growth factors that act as mediators in the development of this disease might be important therapeutic targets. Nintedanib is a triple-tyrosine kinase inhibitor and a potent antagoni...

journal_title：Respiratory care

authors： Dimitroulis IA

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The clinical implications of fractional exhaled nitric oxide (F(ENO)) measurements in childhood asthma are unclear. We aimed to evaluate the relationship between the level of exhaled nitric oxide and pre-bronchodilator FEV1 and the change in FEV1 after bronchodilator in children with asthma. METHODS:This wa...

journal_title：Respiratory care

authors： Grzelewski T,Majak P,Jerzyńska J,Stelmach W,Stelmach R,Janas A,Grzelewska A,Witkowski K,Makandjou-Ola E,Stelmach I

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:In patients suffering from brain injury, end-tidal PCO2 (PETCO2 ) monitoring is controversial, but transcutaneous PCO2 (PtcCO2 ), which is noninvasive and utilizes immediate display, may be an alternative method. We hypothesized that PtcCO2 would be more accurate than PETCO2 for monitoring PaCO2 in patients ...

journal_title：Respiratory care

authors： Rosier S,Launey Y,Bleichner JP,Laviolle B,Jouve A,Malledant Y,Seguin P

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Inhaled medications are the mainstay of treatment for maintenance of lung health in patients with cystic fibrosis (CF). Compressor/nebulizer units are used an average of 100-120 min/d by patients with CF. Each compressor/nebulizer has unique flow/pressure characteristics that affect particle size distributio...

journal_title：Respiratory care

authors： Awad S,Williams DK,Berlinski A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Protective ventilation implementation requires the calculation of predicted body weight (PBW), determined by a formula based on gender and height. Consequently, height inaccuracy may be a limiting factor to correctly set tidal volumes. The objective of this study was to evaluate the accuracy of different met...

journal_title：Respiratory care

authors： Bojmehrani A,Bergeron-Duchesne M,Bouchard C,Simard S,Bouchard PA,Vanderschuren A,L'Her E,Lellouche F

更新日期：2014-07-01 00:00:00

abstract：:The development and evolution of the endotracheal tube (ETT) have been closely related to advances in surgery and anesthesia. Modifications were made to accomplish many tasks, including minimizing gross aspiration, isolating a lung, providing a clear facial surgical field during general anesthesia, monitoring laryngea...

journal_title：Respiratory care

authors： Haas CF,Eakin RM,Konkle MA,Blank R

更新日期：2014-06-01 00:00:00

abstract：INTRODUCTION:Patients receiving invasive mechanical ventilation with an endotracheal tube (ETT) can often benefit from pharmaceutical aerosols; however, drug delivery through the ventilator circuit is known to be very inefficient. The objective of this study was to improve the delivery of aerosol through an invasive me...

journal_title：Respiratory care

authors： Longest PW,Azimi M,Golshahi L,Hindle M

更新日期：2014-05-01 00:00:00

abstract：INTRODUCTION:There is a need to develop simple, noninvasive, and sensitive outcome measures for respiratory therapy. Adventitious respiratory sounds (ie, crackles and wheezes) can be objectively characterized with computerized respiratory sound analysis (CORSA) and have been shown to contribute for diagnosis purposes; ...

journal_title：Respiratory care

authors： Marques A,Oliveira A,Jácome C

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:The nasopharyngeal tube (NT) is a potential interface for noninvasive ventilation (NIV) available in all health care centers. The aim of the study was to describe our experience in the use of the NT for bi-level NIV in infants and its effectiveness. METHODS:Prospective observational study from January 2007 ...

journal_title：Respiratory care

authors： Velasco Arnaiz E,Cambra Lasaosa FJ,Hernández Platero L,Millán García Del Real N,Pons-Òdena M

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:The diagnosis of tuberculous pleural effusion (TBPE) has some limitations. We studied the efficacy of interleukin-27 (IL-27) in the diagnosis of TBPE. METHODS:We measured IL-27, adenosine deaminase (ADA), ADA-2, interferon-gamma (IFNγ), and the ADA·IL-27 and ADA-2·IL-27 products in all the pleural effusion ...

journal_title：Respiratory care

authors： Valdés L,San José E,Ferreiro L,Golpe A,Gude F,Álvarez-Dobaño JM,Pereyra MF,Toubes ME,González-Barcala FJ

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension is frequently associated with parenchymal lung disease. We evaluated the association between spirometry values and pulmonary artery systolic pressure (PASP) in young subjects without lung disease METHODS:: We studied applicants to the Israeli Air Force, who undergo routine evaluation ...

journal_title：Respiratory care

authors： Grossman A,Benderly M,Prokupetz A,Gordon B,Kalter-Leibovici O

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Existing models developed to predict 30 days readmissions for pneumonia lack discriminative ability. We attempted to increase model performance with the addition of variables found to be of benefit in other studies. METHODS:From 133,368 admissions to a tertiary-care hospital from January 2009 to March 2012,...

journal_title：Respiratory care

authors： Mather JF,Fortunato GJ,Ash JL,Davis MJ,Kumar A

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The human respiratory airway undergoes dramatic growth during infancy and childhood, which induces substantial variability in air flow pattern and particle deposition. However, deposition studies have typically focused on adult subjects, the results of which cannot be readily extrapolated to children. We dev...

journal_title：Respiratory care

authors： Xi J,Si X,Zhou Y,Kim J,Berlinski A

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:To maximize the likelihood of successful long-term mechanical ventilation (MV) in patients with neuromuscular diseases, ventilator characteristics and settings must be chosen carefully, taking into account both medical requisites and the patient's preference and comfort. OBJECTIVES:To evaluate patients' kno...

journal_title：Respiratory care

authors： Lofaso F,Prigent H,Tiffreau V,Menoury N,Toussaint M,Monnier AF,Stremler N,Devaux C,Leroux K,Orlikowski D,Mauri C,Pin I,Sacconi S,Pereira C,Pépin JL,Fauroux B,Association Française Contre les Myopathies research group.

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Nebulized therapy is commonly used in spontaneously breathing tracheostomized patients, despite a lack of recommended devices and techniques. I compared albuterol dose delivered to a model of spontaneously breathing children with tracheostomy, using different nebulizers, tracheostomy tube sizes, inhalation t...

journal_title：Respiratory care

authors： Berlinski A

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The value of impulse oscillometry (IOS) for bronchial provocation testing is poorly defined. We investigated the positive threshold derived from the parameters and diagnostic power of IOS for asthma with the leukotriene D(4) bronchial provocation test. METHODS:We enrolled 62 subjects with asthma and 21 heal...

journal_title：Respiratory care

authors： Guan WJ,Zheng JP,Gao Y,Jiang CY,Shi X,Xie YQ,Liu QX,Jiang M,An JY,Yu XX,Liu WT,Zhong LP,Wu ZP,Zhong NS

更新日期：2013-12-01 00:00:00

abstract：:The treatment of choice for patients with respiratory failure of neuromuscular origin, especially in patients with hypercapnic respiratory acidosis, is noninvasive ventilation (NIV). Endotracheal intubation and invasive ventilation are indicated for patients with severe respiratory compromise or failure of NIV. In rec...

journal_title：Respiratory care

authors： Díaz-Lobato S,Folgado MA,Chapa A,Mayoralas Alises S

更新日期：2013-12-01 00:00:00

abstract：:Initial management of patients with difficult-to-treat asthma must begin with confirmation of the diagnosis. We present 2 cases of tracheal disease misdiagnosed as difficult-to-treat asthma. After systemic evaluation, tracheomalacia and tracheobronchial narrowing due to diffuse calcification of the cartilaginous rings...

journal_title：Respiratory care

authors： Alici IO,Kar Kurt O,Dursun AB,Yilmaz A,Erkekol FO

更新日期：2013-11-01 00:00:00

abstract：:Gorham syndrome is a rare disease that presents as progressive osteolysis, and may affect any part of the skeleton. The pathologic process involves the replacement of normal bone by aggressively expanding but non-neoplastic vascular tissue, resulting in massive osteolysis of the adjacent bone. If the spine and ribs ar...

journal_title：Respiratory care

authors： Huang SY,Lee YM,Tzeng ST,Su CP,Huang SF,Wu YK,Lan CC

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The Nippy Clearway is a new mechanical insufflation-exsufflation device used to assist cough. METHODS:We compared the peak expiratory flow (PEF) with the Nippy Clearway versus the CoughAssist in a bench experiment. The relationship between PEF and pressure at the airway opening during exsufflation (minimum ...

journal_title：Respiratory care

authors： Porot V,Guérin C

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Patterns of pulmonary function tests (PFTs) and flow-volume loops among patients with clinically important tracheobronchomalacia (TBM) are not well described. Small studies suggest 4 main flow-volume loop morphologies: low maximum forced expiratory flow, biphasic expiratory curve, flow oscillations, and notc...

journal_title：Respiratory care

authors： Majid A,Sosa AF,Ernst A,Feller-Kopman D,Folch E,Singh AK,Gangadharan S

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To describe the self-expanding endobronchial occluder, as utilized in bronchoscopic lung volume reduction, with a 36 month follow-up procedure. METHODS:Twenty-three subjects with severe emphysema were recruited and underwent flexible bronchoscopic placement of self-expanding endobronchial occluders. Outcomes...

journal_title：Respiratory care

authors： Song L,Zhao F,Ti X,Chen W,Wang G,Wu C,Li Y

更新日期：2013-08-01 00:00:00

abstract：:Pulmonary hypertension (PH) is a common consequence of COPD. It has been speculated that patients showing serious PH and vascular remodeling without severe airway obstruction might benefit from vasoactive treatment. There is no approved drug available for COPD-induced PH. Most trials assessing the efficacy of vasoacti...

journal_title：Respiratory care

authors： Held M,Jany BH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Calculation of physiologic dead space (dead space divided by tidal volume [VD/VT]) using the Enghoff modification of the Bohr equation requires measurement of the partial pressure of mean expired CO2 (PĒCO2) by exhaled gas collection and analysis, use of a metabolic analyzer, or use of a volumetric CO2 monit...

journal_title：Respiratory care

authors： Siobal MS,Ong H,Valdes J,Tang J

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea is a disorder characterized by recurrent obstruction of the upper airways during sleep. The high prevalence of this disease led to proposed new strategies based on the home evaluation and management of patients. OBJECTIVE:To compare home unattended portable monitoring and automatic C...

journal_title：Respiratory care

authors： Tedeschi E,Carratù P,Damiani MF,Ventura VA,Drigo R,Enzo E,Ferraresso A,Sasso G,Zambotto FM,Resta O

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Current literature has been inconsistent in demonstrating that minimizing the duration of mechanical ventilation in very-low-birth-weight (VLBW) newborns reduces lung damage. OBJECTIVE:To determine if introduction of bubble nasal CPAP (bnCPAP), early surfactant treatment, and rapid extubation (combined bnCP...

journal_title：Respiratory care

authors： Friedman CA,Menchaca RC,Baker MC,Rivas CK,Laberge RN,Rios EH,Haider SH,Romero EJ,Eason EB,Fraley JK,Woldesenbet M

更新日期：2013-07-01 00:00:00

abstract：:Mechanically ventilated patients in respiratory failure often require adjunct therapies to address special needs such as inhaled drug delivery to alleviate airway obstruction, treat pulmonary infection, or stabilize gas exchange, or therapies that enhance pulmonary hygiene. These therapies generally are supportive in ...

journal_title：Respiratory care

authors： Kallet RH

更新日期：2013-06-01 00:00:00

abstract：:The presence of bronchiectasis (BR) in patients with rheumatoid arthritis (RA) has been recognized for many decades; nevertheless, little research has been undertaken in this area. It is important to recognize that BR coexistent with RA differs from the other types of BR. The purpose of this descriptive review was to ...

journal_title：Respiratory care

authors： Wilczynska MM,Condliffe AM,McKeon DJ

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Electrical impedance tomography measures changes in lung impedance, which are mainly related to changes in lung volume. We used electrical impedance tomography to investigate the effects of high-flow nasal cannula (HFNC) and body position on global and regional end-expiratory lung impedance variation (ΔEELI)...

journal_title：Respiratory care

authors： Riera J,Pérez P,Cortés J,Roca O,Masclans JR,Rello J

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The contribution of the central respiratory drive in the hypercapnic respiratory failure of neuromuscular diseases (NMD) is controversial. OBJECTIVE:To compare the CO2 response and the duration of weaning of mechanical ventilation between a group of NMD patients and a group of quadriplegic patients due to I...

journal_title：Respiratory care

authors： Rialp G,Raurich JM,Llompart-Pou JA,Ayestarán I,Ibáñez J

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:There is paucity of information on the weaning of nasal CPAP (NCPAP) in preterm infants. As the weaning from NCPAP can be gradual or sudden, we wanted to determine which of the 2 methods was better. METHODS:A prospective randomized trial was conducted to compare the success of weaning from NCPAP when using ...

journal_title：Respiratory care

authors： Rastogi S,Wong W,Gupta A,Bhutada A,Deepa Rastogi.,Maimonides Neonatal Group

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Self-management education is associated with improvement in quality of life and reduction of hospital admissions. Nevertheless, the data are insufficient to formulate clear recommendations regarding the type and content of education programs for COPD patients, and few data are available on knowledge of the d...

journal_title：Respiratory care

authors： Paneroni M,Clini E,Crisafulli E,Guffanti E,Fumagalli A,Bernasconi A,Cabiaglia A,Nicolini A,Brogi S,Ambrosino N,Peroni R,Bianchi L,Vitacca M

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Definite diagnosis of transudative or exudative pleural fluids often presents a diagnostic dilemma. The aim of this study was to evaluate whether amino-terminal brain natriuretic peptide (NT-proBNP) levels in pleural fluid has a diagnostic value for discriminating heart-failure-related pleural effusions from...

journal_title：Respiratory care

authors： Cincin A,Abul Y,Ozben B,Tanrikulu A,Topaloglu N,Ozgul G,Karakurt S,Oktay A

更新日期：2013-02-01 00:00:00

abstract：:Home oxygen therapy equipment options have increased over the past several decades, in response to innovations in technology, economic pressure from third-party payers, and patient demands. The delivery of oxygen in the home has evolved from packaged gas systems containing 99% United States Pharmacopeia oxygen provide...

journal_title：Respiratory care

authors： McCoy RW

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Blow-by, a common form of nebulizer therapy, in which the device is held away from a child's face, has been dismissed as ineffective because studies have demonstrated incremental aerosol drop-off with increasing distances from the face. Many of these studies do not take into account differences among nebuliz...

journal_title：Respiratory care

authors： Mansour MM,Smaldone GC

更新日期：2012-12-01 00:00:00

abstract：:We present a patient with acute-onset dyspnea and unexplained severe hypoxemia. No signs of severe cardiopulmonary disease, pulmonary arterial hypertension, or pulmonary embolism were present. The patient was diagnosed with hepatopulmonary syndrome, since liver disease of alcoholic origin was present, markedly increa...

journal_title：Respiratory care

authors： Madsen PH,Hess S,Madsen HD

更新日期：2012-11-01 00:00:00

abstract：:Dexmedetomidine is a selective alpha-2 receptor agonist that possesses both sedative and analgesic properties, with minimal respiratory depression. We report the successful administration of dexmedetomidine on a 16-year-old primigravida woman that allowed the patient to tolerate application of bi-level positive airwa...

journal_title：Respiratory care

authors： Duan M,Lee J,Bittner EA

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:It is well established that the work rate increment size affects the duration of test and physiological responses to exercise during cycling in patients with COPD. However, this has never been tested for incremental step tests. OBJECTIVE:To compare the exercise tolerance time, cardiopulmonary stress, and p...

journal_title：Respiratory care

authors： de Andrade CH,de Camargo AA,de Castro BP,Malaguti C,Dal Corso S

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Percutaneous dilational tracheostomy (PDT) can potentially lead to hypoxia and alveolar derecruitment. The aim of this prospective study was to evaluate the efficacy of performing a recruitment maneuver (RM) before tracheostomy, in order to improve oxygenation. METHODS:We enrolled 29 eligible trauma patient...

journal_title：Respiratory care

authors： Franchi F,Cubattoli L,Faltoni A,Scolletta S,Falciani E,Mastrocinque E,Giomarelli P,Patroniti N

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Elevated dead space fraction (the ratio of dead space to tidal volume [V(D)/V(T)]) is a feature of ARDS. PEEP can partially reverse atelectasis, prevent alveoli recollapse, and improve lung compliance and gas exchange in patients with ARDS. However, whether V(D)/V(T) variables have a close relationship with ...

journal_title：Respiratory care

authors： Fengmei G,Jin C,Songqiao L,Congshan Y,Yi Y

更新日期：2012-10-01 00:00:00